Targeting obesity related microenvironment factors for biomarkers avenues of early female reproductive cancer detection

Principal Investigators: Dr Mona Shehata, University of Cambridge; Prof Emma Crosbie, University of Manchester and Dr Laura Heiser, Oregon Health & Science University
Funded by: ACED Pilot Award 2020

Drs Shehata and Heiser and Prof Crosbie will use clinically relevant human breast and endometrial organoid models to test the contribution of obese-related microenvironment components towards cancer initiation. The team's work will allow for the future development of biomarkers for the early detection of breast and endometrial cancers in obese and post-menopausal women.