Proof of Principle - Hyperspectral endoscopy imaging for early detection of precancerous lesions in average risk and inflammatory bowel disease (IBD) patients

Principal Investigators: Dr Sarah Bohndiek, (Cambridge), Dr Liana Tsikitis & Sarah Diamond (OHSU)

Funded by: OHSU-CRUK SPARK Award 2018

Dr Sarah Bohndiek and Dr Jonghee Yoon (Cambridge), and Dr Liana Tsikitis (Department of Surgery, OHSU) and Dr Sarah Diamond (OHSU) have received a Spark award to collaborate on the project entitled: ‘hyperspectral endoscopy imaging for early detection of precancerous lesions in average risk and inflammatory bowel disease (IBD) patients’.

The aim of the project is to investigate hyperspectral endoscopy as a visualisation aid for lesions, in particular flat polyps, in the colon that may be missed by the current colonoscopy methods used (high-definition white light endoscopy). In addition, the team will examine the use of hyperspectral imaging to improve visualisation of any residual polyp tissue following a polypectomy, which may be a contributing factor to interval colorectal cancer development. The technology will also be investigated as an alternative means of detecting dysplasia in patients with inflammatory bowel disease, a known risk-factor for colorectal cancer.