Novel tools for molecular imaging of pancreatic preneoplasia

Principal Investigators: Prof Kevin M Brindle, University of Cambridge and Prof H Tom Soh, Stanford University
Funded by: ACED Pilot Award 2020

Pancreatic cancer is often not diagnosed until at an advanced and incurable stage. Most cancers are known to remodel their glycosylation patterns on their surfaces. In this work, Professors Bridle and Soh will develop synthetic reagents that target cell surface glycans for early pancreatic cancer detection, which may also enable potentially curative surgical intervention. The aim is to develop novel molecular imaging tools that can provide key clinical information on early pancreatic cancer development.