Analysing menstrual fluid at the single cell level and assaying its suitability for the derivation of epithelial organoids

Principal Investigator: Dr Angela Goncalves, Wellcome Trust Sanger Institute

Co-Investigator: Dr Daniel Gaffney, Cambridge Cardiovascular

Funded by: CRUK Cambridge Centre Early Detection Programme Gynaecological Cancers Pump Priming Award 2017

The aim of this project is to demonstrate the feasibility and utility of using menstrual fluid collected on day 2 of the menstrual cycle for diagnostics and research. We will characterise cell viability, the cell types present and determine whether MF is a suitable source of cells for the establishment of epithelial cell cultures (epithelial organoids) for in vitro studies.