Past Events

Title

Lectures in Cancer Biology and Medicine - Michaelmas Term 2019

Date: Every Thursday, starting on 24 October
Time: 09:30 - 10:30
Venue: Clinical School Lecture Theatre 2

These talks aim to give a general introduction to cancer biology and medicine and all students and staff are welcome to attend.

Thursday 28 November: Professor Brian Huntly, Department of Haematology.
Cancer stem cells, evolution and heterogeneity
Thursday 5 December: Professor Steve Jackson, The Gurdon Institute.
DNA repair: from mechanistic insights to therapeutic applications in cancer
Thursday 12 December: Dr Jacqui Shields, MRC Cancer Unit.
Exploring the role of the tumour microenvironment: what do the other cells do?

Early Detection Christmas Networking Social

Date: Wednesday 11th December 2019
Time: 17:30 - 19:30
Venue: Maxwell Centre, JJ Thomson Avenue, Cambridge CB3 0HE

Join the Cancer Research UK Cambridge Centre Early Detection programme for their networking Christmas social. With this event we would like to celebrate the ongoing achievements of the Programme and to thank you for your support. There will be festive music, mulled wine and canapés, please register here.

Title

Molecular subtypes and prognostic tests in prostate cancer: reducing clinical interventions and overtreatment

Date: Monday 9th December 2019
Time: 11:30
Venue: Hutchison/MRC Cancer Unit, Cambridge Biomedical Campus, room 1.8/1.9

A talk by Daniel Brewer, Cancer Genetics, Norwich Medical School, University of East Anglia.

The Cancer Genetics team at the Norwich Medical School, UEA, is an interdisciplinary team comprising a mixture of bioinformaticians, clinicians, and lab-based scientists. They have a broad interest in applying cutting-edge analytical and laboratory techniques in translational cancer based molecular studies with the aim of improving patient care, with a particular focus on prostate cancer. In this talk Daniel Brewer will describe work on two projects he is actively pursuing which he hopes will reduce overtreatment and the number of biopsies performed: a prognostic biomarker based on cell free RNA in urine and defining molecular subtypes in prostate cancer.

Click here for more information.

Urological Malignancies Programme Annual Meeting

Date: Thursday 28th November 2019
Time: 09:00 - 18:00
Venue: Homerton College, Hills Road, Cambridge CB2 8PH

A full day meeting to discuss current activities in the Cancer Research UK Cambridge Centre Urological Malignancies Programme. Four sessions are planned:

  • Basic science
  • Early Detection
  • Translational Research
  • Clinical Trials

Title

Breakfast meeting: Using discrete choice experiments to evaluate patient and professional preferences for early detection of cancer

Date: Thursday 14th November 2019
Time: 08:30 - 09:30
Venue: Jeffrey Cheah Restaurant, Puddicombe Way, Cambridge, CB2 0AF

These meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

Professor Steve Morris, RAND Professor of health economics at the Department of Public Health and Primary Care, will open this breakfast meeting on "Using discrete choice experiments to evaluate patient and professional preferences for early detection of cancer".

Title

Cancer Screening and Prevention: Lessons Learned

Date: Friday 8th November 2019
Time: 13:00 - 14:00
Venue: Large Seminar Room, 1st Floor, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge CB2 0SR

Professor Mette Kalager from the Department of Health Management & Health Ecnomics, Institute of Health & Society, University of Oslo will give a talk on cancer screening and prevention. This talk will address how we can give our population the best cancer screening options.

Click here for more information.

Title

Cancer Research UK Business Accelerator Roadshow

Date: Thursday 7th November 2019
Time: 17:00 - 19:00
Venue: CRUK Cambridge Institute Gallery

Cancer Research UK have partnered with two business accelerators, Panacea and Deep Science Ventures, to provide you with training and skills to translate your ideas and discoveries.

The event will include talks from Cancer Research UK on it's new entrepreneurship initiative as well as from Panacea & Deep Science Ventures explaining how their accelerator schemes can benefit you.

Briefing event for International Alliance for Cancer Early Detection (ACED) funding calls

Date: Tuesday 5th November 2019
Time: 13:15 - 14:30
Venue: CRUK Cambridge Institute room 215 A&B

The Early Detection Programme will be hosting Dr David Crosby, Head of Early Detection Research and Nicole Lyons, ACED Programme Manager at Cancer Research UK for a briefing and Q&A on the upcoming funding calls from ACED (previously ICED).

David and Nicole will also be available from 2.30pm - 4pm on the 5th November for 1:1 meetings with researchers - please email if you are interested in reserving a slot to discuss your project ideas. If you are unable to attend in person you could alternatively schedule a phone call with David and Nicole during this time.

The ACED grant calls will be open in mid October when full details will be made available:

• Pilot funding up to £200,000 for 1 year

• Project funding from £200,000 to £800,000 for 3 years (expressions of interest invited)

• Training and skills development funding of up to £50,000 for researchers to visit other Alliance Centres for up to 4 months to support travel and accommodation

All projects funded by the Alliance will involve at least two member Centres (UK-UK or UK-US), with an aim that at least 50% of projects will be transatlantic. A press release announcing ACED US partners is scheduled for mid October.

Please note that Pilot and Project grants are only open to Cambridge University PI/Group Leaders to apply, but the training and skills development grants are applicable for all levels of University researchers. This is an open call but projects aligning with the core strategic themes of the Alliance will be prioritised. For further information please contact the Early Detection Programme Manager Dr Wendy Alderton 01223 762588 or Research Translation Manager Dr Cat Fitzpatrick 07539 430956

Title

Collaborating with the Cancer Research UK-AstraZeneca Antibody Alliance Laboratory to Develop Diagnostic Antibodies

Date: Monday 28th October 2019
Time: 17:30 - 19:00
Venue: Clinical School Seminar Room 10, Cambridge Biomedical Campus, Cambridge CB2 0SP

At our multidisciplinary networking events we pair a clinician with an industry representative or a STEM scientist to speak for 15-20 minutes each on their work. This time the format is slightly different as the topic is "Collaborating with the Cancer Research UK-AstraZeneca Antibody Alliance Laboratory to Develop Diagnostic Antibodies".

Following the talks there will be opportunity for networking over refreshments.

Speakers:
Maria Groves, Head of Laboratory, Associate Director AstraZeneca
Julie Little, Strategic Alliance Executive, CRUK
Denice Chan, Senior Scientist, CRUK
Lisa Ruff, PhD student, CRUK

Title

CRUK - AACR Joint Conference on Engineering and Physical Sciences in Oncology 2019

Date: Tuesday 15 - Thursday 17th October 2019
Venue: Radisson Blu Portman, Marylebone, London

The Cancer Research UK–AACR Joint Conference on Engineering and Physical Sciences in Oncology is taking place in London this autumn where alliances between cancer researchers and leading scientists from engineering and physical sciences backgrounds will be sparked.

The multidisciplinary programme will explore new ways to transform our understanding of biology and to better detect and treat cancer, enabling expert speakers to address some of the toughest challenges in cancer research from a variety of perspectives. You’ll have ample opportunity to interact with leaders in their field, while sessions will equip you with valuable insights into building effective alliances across disciplines.

Our programme leader, Dr Sarah Bohndiek, will be speaking in the ‘state-of-the-art cancer detection technology’ session.

Title

Interrogating the impact of the microenvironment of therapeutic response in breast cancer

Date: Monday 14th November 2019
Time: 11:00 - 12:00
Venue: CRUK Cambridge Institute Auditorium

Dr. Korkola is Group Leader at OHSU School of Medicine. Korkola's research work is primarily on breast cancer, with a focus on how interactions with microenvironment impact the phenotype of cancer cells, emphasising those that alter the way cells respond to therapy. The Korkola Lab also is interested in understanding the mechanisms of resistance induced by extrinsic and intrinsic factors and developing multi-drug combinations to overcome resistance and improve patient outcomes.

The Early Detection of Cancer Conference

Date: Tuesday 24 - Thursday 26th September 2019
Venue: Frances C. Arrillaga Alumni Center, Stanford, California

Canary Center at Stanford, Cancer Research UK and the OHSU Knight Cancer Institute, present the Early Detection of Cancer Conference series. The annual Conference brings together experts in early detection from multiple disciplines to share ground breaking research and progress in the field.

The Conference is part of a long-term commitment to invest in early detection research, to understand the biology behind early stage cancers, find new detection and screening methods and enhance uptake and accuracy of screening.

Title

The Global Health Tech Ecosystem - Constructors and Disruptors

Date: Tuesday 17th September 2019
Time: 13:00 - 14:00
Venue: Postdoc Centre, Clifford Allbutt Building, Biomedical Campus

A seminar by Dr Andy Richards, CBE, business angel and entrepreneur. Innovation in healthcare has been based largely on an established ecosystem with longstanding relationships and well known players translating and commercialising the life-sciences. However, that is all changing as data becomes a major value driver and the tech world increasingly focusses on healthcare bringing new entrants, with different approaches and business models. In this battle for the future of healthcare, there will be winners, losers with many mistakes made, but healthcare will change as a result. This talk will provide a big picture view of how these innovation ecosystems are approaching healthcare and how they may be able to make important progress in precision medicine, prevention, diagnosis and the early detection of disease.

Title

Breakfast meeting: Metabolic imaging and radiomics – new ways of probing tumour biology

Date: Thursday 12th September 2019
Time: 08:30 - 09:30
Venue: Clinical School Restaurant

These meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

The September meeting is a collaboration with the CRUK Cambridge Centre Urological Malignancies Programme. Dr Stephan Ursprung will open this meeting on "Metabolic imaging and radiomics – new ways of probing tumour biology".

Title

International Summer School

Date: Monday 15th July 2019 - Thursday 18th July 2019
Venue: Robinson College, Grange Road, Cambridge CB3 9AN, UK

We present the first international summer school on discovery and development of diagnostics for the early detection of cancer. The summer school is aimed at those who are developing new technologies and interventions for the early detection of cancer and those who are interested in exploring this rapidly expanding and exciting field and is open to academic, corporate and student delegates.

Please click here for more information about the International Summer School.

Title

Early Detection Garden Party

Date: Monday 8th July 2019
Time: 17:00 - 19:00
Venue: Trinity College, Fellows' Bowling Green, Trinity Street, Cambridge CB2 1TQ

Please join us to celebrate the ongoing achievements of the CRUK Cambridge Centre Early Detection Programme and to thank you for your support.

Light refreshments will be served.

Title

Seminar: Miniature optical endoscopes for early detection of ovarian cancer

Date: Wednesday 19th June 2019
Time: 15:30 - 16:30
Venue: Clinical School Seminar Lecture Theatre 2, Cambridge Biomedical Campus, Cambridge CB2 0SP

Jennifer Kehlet Barton, PhD, Professor, Biomedical Engineering, University of Arizona

Talk Abstract: Optical imaging techniques have been shown to be highly sensitive to early stages of cancer. We have examined techniques including optical coherence tomography, fluorescence imaging, and multiphoton imaging in mouse models of ovarian cancer as well as human samples of uterine tube and ovary. These studies suggest that ovarian cancer is detectable at microscopic as well as macroscopic scales. To implement early detection in vivo, a method of reaching the ovaries and fallopian tubes in a minimally invasive fashion must be found. We are developing endoscopes which travel a variety of paths through the female reproductive system, and incorporate one or more of the optical modalities.

Speaker Bio: Jennifer Barton received the BS and MS degrees in electrical engineering from the University of Texas at Austin and University of California Irvine, respectively. She worked for McDonnell Douglas (now Boeing) on the Space Station program before returning to The University of Texas at Austin to obtain the PhD in Biomedical Engineering in 1998. She is currently Professor of Biomedical Engineering, and Director of the BIO5 Institute, a collaborative research institute dedicated to solving complex biology-based problems affecting humanity.

Barton develops miniature endoscopes that combine multiple optical imaging techniques, particularly optical coherence tomography and fluorescence spectroscopy. She evaluates the suitability of these endoscopic techniques for detecting early cancer development in patients and pre-clinical models. She has a particular interest in the early detection of ovarian cancer, the most deadly gynecological malignancy. Additionally, her research into light-tissue interaction and dynamic optical properties of blood laid the groundwork for a novel therapeutic laser to treat disorders of the skin’s blood vessels. She is a fellow of SPIE- the International Optics Society, and a fellow of the American Institute for Medical and Biological Engineering.

Title

Breakfast meeting: Translating technology to clinical application

Date: Thursday 13th June 2019
Time: 08:30 - 09:30
Venue: Clinical School Restaurant

These meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

Professor Andrew Flewitt will open this meeting on "Translating technology to clinical application".

Early Detection Multidisciplinary Networking Event: Breast screening approaches

Date: Monday 3rd June 2019
Time: 17:30-19:00
Venue: Clinical School Seminar Room 10, Cambridge Biomedical Campus, Cambridge CB2 0SP

At our multidisciplinary networking events we pair a clinician with an industry representative or a STEM scientist to speak for 15-20 minutes each on their work and where it might be relevant to early cancer detection, and where greater collaboration could assist. At this event the focus will be on breast cancer. Following the talks there will be opportunity for networking over refreshments.

Speakers:
Professor Fiona J. Gilbert - Professor of Radiology, University of Cambridge School of Clinical Medicine and Honorary Consultant Radiologist, Addenbrooke’s Hospital, Cambridge. University Hospitals NHS Foundation Trust.
"Breast Screening – a risk adapted imaging approach"

&

Dr Christopher E. Tromans - Science and Engineering Manager (Europe), Volpara Solutions Ltd.
"
Using volumetric breast density to personalise breast screening."

Title

Seminar: Error-corrected sequencing for minimal residual disease detection in leukemia and bone marrow transplantation

Date: Friday 24th May 2019
Time: 15:00 - 16:00
Venue: CRUK Cambridge Institute, Room 215

Talk abstract: Following chemotherapy, the quantitative assessment of residual cancer, so-called minimal residual disease, identifies individuals that require more intensive, and often targeted, therapy to overcome their disease. However, high-throughput sequencing has only provided a limited role in this endeavor due to a high rate of systematic errors that confound detection of low-frequency or subclonal populations, which can expand and reduce overall survival. Significant improvements in the precision of high-throughput sequencing can be achieved through error-corrected sequencing (ECS), with a limit of detection of 0.0001. These methods have revealed extensive physiologic clonal hematopoietic diversity that must be differentiated from disease processes to enable appropriate therapeutic selection. This presentation will discuss the application of ECS to define normal physiologic clonal hematopoiesis as well as the application of ECS to improve outcomes in myeloid leukemia and bone marrow transplantation.

Speaker information: Todd Druley, Washington University Medical School, is a paediatric oncologist who has been a pioneer of Error Correctable Sequencing to probe ultra low frequency variants in the detection of Minimal Residual Disease and Clonal Haematopoiesis. He has recently been appointed CTO at Archer Dx a molecular cancer diagnostics company in the US.

Title

Pint of Science: Combating cancer

Date: Thursday 22nd May 2019
Time: 19:00 - 21:30
Venue: Granta, 14 Newnham Road. Cambridge CB3 9EX

Early Detection Programme members Dr Christian Frezza and Dr Gahee Park and Early Detection Group Leader Dr Charlie Massie will speak at this event.

Dr Christian Frezza will talk about the current understanding of the nutrients that cancer cells use to grow and proliferate, and how this insight can improve our strategies for detecting and treating cancer. Dr Charlie Massie and Dr Gahee Park's talk is entitled "Can we develop blood tests for cancer early detection and what might the consequences be?".

For more information and to register for this event, please click here.

Title

Breakfast meeting: Can we reach national cancer targets on early stage at diagnosis by eliminating demographic disparities?

Date: Thursday 11th April 2019
Time: 08:30 - 09:30
Venue: Clinical School Restaurant

These meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

Matthew Barclay, Research Assistant/Statistician at THIS.Institute, will open this breakfast meeting on "Can we reach national cancer targets on early stage at diagnosis by eliminating demographic disparities?".

Seminar: Applications of big data and mathematical modeling to accelerating biomarker discovery

Date: Tuesday 2nd April 2019
Time: 12:00-13:00
Venue: Clinical School Seminar Room 17, Cambridge Biomedical Campus

ALL WELCOME

Visiting Researcher, Prof Parag Mallick, Associate Professor (Research) of Radiology (Cancer Early Detection - Canary Center) will give a seminar on Applications of big data and mathematical modeling to accelerating biomarker discovery.

Talk abstract:

Low cost diagnostic strategies for cancer early detection and treatment strategy personalization are expected to radically improve patient outcomes and decrease healthcare costs. One important diagnostic strategy infers the presence, progression, or drug response of a cancer from measurements of the abundance of one or more circulating protein biomarkers. Unfortunately, the development of circulating biomarker-based diagnostic strategies is bottlenecked by the failure of existing workflows to discover usable biomarkers. We recently observed that the majority of these failures may originate with the false assumption that a protein's tumor and blood abundance are trivially concordant. Contrary to prior belief, we have demonstrated that the relationship between a protein's tumor and blood abundance is highly discordant. We hypothesize that the tumor-blood relationship is driven by combinations of non-linear processes, which lead some proteins to not shed from the tumor into the blood or, once shed drive to not persist (possibly due to slow intratumoral diffusion kinetics or fast degradation kinetics). Despite the significant need for biomarkers, fundamental questions remain about the mechanisms governing shedding and persistence dynamics - a knowledge gap bottlenecking biomarker discovery. By integrating data from large-scale studies with a novel mathematical model, we have recently developed a new software tool that is able to prioritize markers based upon their likely circulating kinetics. In addition, we have begun the development of a new resource to coalesce the diverse existing knowledge about potential candidates.

Speaker biography:

Dr. Parag Mallick is an Associate Professor at Stanford University. Originally trained as an engineer and biochemist, his research spans computational and experimental systems biology, cancer biology and nanotechnology. Dr. Mallick received his undergraduate degree in Computer Science from Washington University in St. Louis. He then obtained his Ph.D. from UCLA in Chemistry & Biochemistry, where he worked with Dr. David Eisenberg. He completed Post-Doctoral studies at The Institute for Systems Biology, in Seattle, WA with Dr. Ruedi Aebersold. Beyond studying fundamental disease mechanisms, his group has been exploring ways to exploit large-scale data and mathematical modeling to enable personalized and predictive medicine.

Title

Early Detection Multidisciplinary Networking Event: focus on liver cancer

Date: Monday 25th March 2019
Time: 17:30-19:00
Venue: Clinical School Seminar Room 1, Cambridge Biomedical Campus

At this first multidisciplinary networking event of 2019 we will hear from Dr Victoria Snowdon, Consultant Hepatologist at Addenbrooke's Hospital Liver Unit, who will speak on Early detection in HCC – where we are and where we need to be.

Dr Andrea Murray, Chief Operational Scientist at Oncimmune Ltd, will speak on "Early detection of liver cancer through measurement of cancer auto-antibody panels"

Refreshments will be provided.

Title

Making algorithms trustworthy

Date: Thursday 21th March 2019
Time: 19:30 - 20:30
Venue: Mill Lane Lecture Rooms, 8 Mill Lane, CB2 1RW

Algorithms are being increasingly deployed to make judgements about sensitive parts of our lives, but how do we check how their conclusions were arrived at, and if they are valid and fair? Professor David Spiegelhalter looks at efforts to make algorithms transparent and trustworthy, illustrated with explanation facilities on systems making predictions for people with cancer. More information

Title

Seminar: Stem Cells in Cancer and Aging

Date: Friday 15th March 2019
Time: 13:00-14:00
Venue: Clifford Allbutt Lecture Theatre, Cambridge Biomedical Campus

ALL WELCOME

Manuel Collado is an investigator at the Health Research Institute of Santiago de Compostela (IDIS). Manuel did a postdoc stay at the Ludwig Institute for Cancer Research in London, UK, and at Memorial Sloan-Kettering Cancer Center in New York, USA, before returning to Spain to join the laboratory of Manuel Serrano at the Spanish National Cancer Research Centre (CNIO), in Madrid. He moved to Santiago de Compostela in 2012 to create the laboratory of “Stem Cells in Cancer and Aging”. Manuel has published close to 60 peer-reviewed articles on tumor suppression, cell senescence and cellular reprogramming in top journals such as Nature, Cell, Cell Stem Cell, PNAS, Cancer Cell, Aging Cell, EMBO J, etc. He is also the author of seminal reviews on the topic of senescence in Cell and in Nature Reviews Cancer. He is a member of the Spanish National Network of Excellence on Cellular Senescence and he is part of the Steering Committee of the International Cell Senescence Association (ICSA).

Title

Seminar: Deciding when to visit the GP with cancer symptoms: the Goldilocks Zone differs in England, Denmark and Sweden

Date: Monday 11th March 2019
Time: 2.00pm-3.00pm
Venue: Strangeways Research Laboratory, Dorothy and Thomas Senior Rooms, 2 Worts' Causeway, Cambridge CB1 8RN

The Primary Care Unit invites you to a seminar given by Professor Sue Ziebland, Professor of Medical Sociology and Director of HERG (Health Experiences Research Group), Programme Director for NIHR Research for Patient Benefit programme and Professor of Medical Sociology in the Nuffield Department of Primary Care Health Sciences at the University of Oxford.

Abstract:

The International cancer benchmarking studies have highlighted between country differences in stage of cancer at diagnosis; these are not explained by differences in population awareness of cancer signs and symptoms.

In this talk I will draw on our CRUK/ NAEDI funded qualitative cross country comparative study of accounts of the pre-diagnosis experiences of Swedish, Danish and English people later diagnosed with lung or bowel cancer. The analysis illustrated differences in willingness to consult with symptoms and when to return if symptoms did not resolve. Our understanding was informed by sociologist Robert Merton’s work on ambivalence and the metaphor of the Goldilocks Zone. I will argue that the study illuminates differences between these three public-funded health systems which have consequences for citizen’s access to care and stage of diagnosis.

Title

Cancer Research UK Cambridge Institute International Symposium

Date: Thursday 7 - Friday 8 March 2019
Time: All day
Venue: Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE

The CRUK Cambridge Institute is hosting their International Symposium. The main theme of the symposium is "Radical approaches to cancer prevention". As well as outstanding keynote speakers, each session will include invited speakers and short talks selected on the basis of scientific merit.

The symposium will include talks on:
- Using new technology to reduce and prevent disease
- Training the immune system
- Preventing cancer through medical intervention
- Preventing cancer through lifestyle and policy

Title

Breakfast meeting: Cost effectiveness of screening for kidney cancer

Date: Thursday 14th February 2019
Time: 08:30 - 09:30
Venue: Clinical School Restaurant

These meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

Sabrina Rossi will open this meeting on "Cost effectiveness of screening for kidney cancer".

5th CRUK Bienniel Early Diagnosis Conference

Date: Tuesday 12th - Wednesday 13th February 2019
Venue: Hilton Birmingham Metropole

The 5th Biennial CRUK Early Diagnosis Research Conference will take place on 12th-13th February 2019 at the Hilton Birmingham Metropole. In the ten years since a national strategy to reduce premature mortality from cancer was developed, great headway has been made in all the UK nations and internationally. The theme of this 10th anniversary conference will be Accelerating early diagnosis evidence into practice.

Title

Early Detection Programme Annual Symposium 2019

Date: Monday 28th January 2019
Time: 10:30 - 15:00
Venue: Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE

The fourth annual symposium from the CRUK Cambridge Centre Early Detection Programme will take place on Monday 28th January 2019. We are delighted to have two Keynote speakers, Bob Steele - Senior Research Professor in Surgical Oncology, University of Dundee and Chair of UK National Screening Committee and Per Hall, Professor of Medical Epidemiology and Biostatistics at the Karolinska Institute and Honorary Consultant Physician, Södersjukhuset, Sweden.

Symposium Booklet 2019 Final

Biomarker Discovery Seminar

Date: Monday 21st January 2019
Time: 12:30-14:00
Venue: Clinical School Lecture Theatre 2, Cambridge Biomedical Campus

We are pleased to be hosting this seminar in conjunction with OLink Proteomics.

We will hear from Dr Xavier Tait, Business Development Manager, on An introduction to biomarker discovery with Olink. This will be followed by a talk from Professor Ulf Gyllensten, Professor of Human Genomics and Molecular Epidemiology, University of Uppsala
on Development of a protein biomarker test for gynaecological cancer.

Speaker Biography

Ulf Gyllensten, PhD. is Professor of Medical Molecular Genetics at the Department of Immunology, Genetics and Pathology, Uppsala University. He has over 250 peer-reviewed publications and has held a large number of prestigious academic positions, including the editorial boards of several international journals, the priority committees of the Swedish Medical Research Council and Swedish Cancer Society, Director of the world renowned Rudbeck Laboratory and currently, Scientific Director of the Science for Life Laboratory in Uppsala. Professor Gyllensten also holds multiple biotechnology patents, is co-founder of the Swedish biotech companies Dechipher Genetics AB and Quantovir AB and has acted as consultant for both Perkin-Elmer and Roche Molecular Systems. His presentation will describe a project with the ultimate aim of developing a simple biomarker test to identify and distinguish between gynecological cancers, as well as providing discrimination among different stages of cancer. The talk will cover both a broad screening approach using over 400 protein markers, and subsequent verification studies using a smaller panel of just over 40 markers.

Early Detection Technology Sharing Forum

Date: Tuesday 4th December 2018
Time: 17:30 - 19:30
Venue: David Dunn Room, Addenbrooke's Hospital (through main hospital concourse entrance), Hills Road, Cambridge CB2 0QQ

An issue that we are constantly hearing about in the application of technology to healthcare is the disconnect between technology providers and clinicians. We are going to address this by hosting an event in the hospital itself, enabling as many clinicians as possible to attend. We have invited four technologists to share their early detection technologies with clinical colleagues in order to stimulate feedback, discussion and the co-creation of ideas. If this event is successful we hope that we can run a series of them in the New Year.

In December we will hear from Prof George Malliaras, Electrical Engineering on New materials and devices for early detection; Dr. Róisín Owens, Chemical Engineering and Biotechnology on Bioelectronic devices for cancer detection; Dr Ljiljana Fruk, Chemical Engineering and Biotechnology on Diagostics/theranostics: Chemistry behind (bio)functionalised nanomaterials, and Professor Andrew Flewitt, Engineering on Using systems-based engineering as a means of addressing clinical needs.

We hope that this event will lead to interesting, two-way discussion and greater collaboration.

Title

Festival of Ideas 2018 seminar: Cancer overdiagnosis - what is it?

Date: Friday 26th October 2018
Time: 17:30 - 18:30
Venue: Eastwood Room,Office of Postdoctoral Affairs, 16 Mill Lane, Cambridge CB2 1SB. Please note the seminar room is in the basement and access is via stairs only.

Many diseases, such as cancer, are easier to treat the earlier they are detected, so it makes sense to test people without symptoms in higher risk groups to see if they have the disease. Unfortunately, it can be hard to detect early-stage disease with accuracy, and even harder to know that our interventions will actually benefit patients. Screening saves lives, but also leads to overdiagnosis and overtreatment.

The CRUK Cambridge Centre Early Detection Programme invites you to join Dr Stephen John, Hatton Lecturer in the Philosophy of Public Health and Dr Maryon McDonald, Fellow in Social Anthropology at Robinson College, Cambridge for a seminar to discuss some of the issues around cancer screening and diagnosis.

CRUK CI seminars in cancer: Towards cancer screening using circulating DNA

Date: Thursday 25th October 2018
Time: 1.00-2.00pm
Venue: Lecture Theatre, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge CB2 0RE

There is much recent interest in the use of circulating DNA in plasma for performing liquid biopsies for cancer. However, most of the published efforts are for the investigation of patients who have already been diagnosed to have cancer. There is much less information on the use of circulating DNA for the screening of cancer. My laboratory has developed the use of circulating Epstein-Barr virus (EBV) DNA as a biomarker for EBV -associated malignancies, especially for nasopharyngeal carcinoma (NPC). We have just completed a large scale trial of using plasma EBV DNA in the screening of NPC in asymptomatic individuals. Our data indicate that using this approach, one can shift the stage distribution at diagnosis from 20% early stage diseases in an unscreened population to 70% early stage diseases in a screened population. Furthermore, NPC subjects whose cancer were detected by plasma EBV DNA screening had a much better prognosis than those NPC patients who were not screened. The implication of this work to cancer screening in the context of NPC and for other cancers will be discussed.

Speaker information:

Professor Dennis Lo, Director of the Li Ka Shing Institute of Health Sciences, the Li Ka Shing Professor of Medicine and Professor of Chemical Pathology of The Chinese University of Hong Kong (CUHK). He is also the Associate Dean (Research) of the Faculty of Medicine of CUHK. Dennis Lo received his Bachelor of Arts degree from the University of Cambridge and the Doctor of Medicine and Doctor of Philosophy degrees from the University of Oxford. Full biography.

Title

The elimination of cervical cancer by 2050 - reality or wishful thinking?

Date: Wednesday 24th October 2018
Time: 17:30
Venue: Yusuf Hamied Theatre in the Yusuf Hamied Centre, Christ's College, New Court

Professor Margaret Stanley OBE (Honorary Fellow of Christ's) will be giving a Lady Margaret Lecture 'The elimination of cervical cancer by 2050 - reality or wishful thinking?'. Click here to read more about this event.

Title

Breakfast meeting: Early Detection - is it "worth it"? The importance of cost-effectiveness in healthcare.

Date: Thursday 11th October 2018
Time: 08:30 - 09:30
Venue: Clinical School Restaurant

These meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

The October meeting will be opened by Dr Ed Wilson, Senior Research Associate in Health Economics & Academic Lead, Cambridge Research Methods Hub, Institute of Public Health on the subject of Early Detection - is it "worth it"? The importance of cost-effectiveness in healthcare.

2018 Early Detection of Cancer Conference

Date: Tuesday 2nd Oct - Thursday 4th Oct 2018
Time: 08:30-15:30
Venue: Portland - Knight Cancer Research Building, 3181 S.W. Sam Jackson Park Road, CR145, Portland, OR 97239

OHSU Knight Cancer Institute, Canary Center at Stanford, and Cancer Research UK present the Early Detection of Cancer Conference 2018. The annual Conference brings together experts in early detection from multiple disciplines to share ground breaking research and progress in the field.

The Conference is part of a long-term commitment to invest in early detection research, to understand the biology behind early stage cancers, find new detection and screening methods and enhance uptake and accuracy of screening. The conference will be held on October 2nd – 4th at the new Knight Cancer Research Building on the campus of OHSU, Portland, Oregon.

Title

Early Detection Pump Priming Project Showcase

Date: Monday 24th September 2018
Time: 17:30 - 19:00
Venue: Maxwell Centre, JJ Thompson Avenue, Cambridge CB3 0HE

We present a showcase of some of the projects funded by the Early Detection Programme. Please join us for some short presentations and the opportunity to network with the project teams. Presentations will be given by:

  • Mr Vincent Gnanapragasam and Prof Andrew Flewitt
  • Dr George Gordon
  • Dr Massi di Pietro
  • Dr Angela Gonçalves
  • Dr Robert Rintoul

Title

Breakfast meeting: How can engaging with health policy support the implementation of research and technology into clinical practice?

Date: Thursday 13th September 2018
Time: 08:30 - 09:30
Venue: Clinical School Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

In September Dr Laura Blackburn, Acting Head of Science at the PHG Foundation, will open the meeting on the subject of: About PHG Foundation: how can engaging with health policy support the implementation of research and technology into clinical practice?

Title

Early Detection Garden Party

Date: Monday 9th July 2018
Time: 17:00 - 18:30
Venue: Trinity College, Fellows' Bowling Green, Trinity Street, Cambridge CB2 1TQ

Please join us to celebrate the ongoing achievements of the CRUK Cambridge Centre Early Detection Programme and the BEST3 Trial and to thank you for your support. Light refreshments will be served.

Title

​Early Detection multidisciplinary networking series event 6: Dr Ferdia Gallagher & Dr Philip Murphy

Date: Monday 25th June 2018  
Time: 17:30 - 19:00 
Venue: Seminar Room 1, Clinical School, Cambridge Biomedical Campus

For this event series we are inviting a STEM scientist or a representative from a relevant local company to pair with a clinical colleague to speak for 15-20 minutes each on their work and where it might be relevant to early cancer detection, and where greater collaboration could assist. 

We have two speakers for this event who will speak on Using new imaging methods to detect cancer.

Dr Ferdia Gallagher - Honorary Consultant Radiologist, Department of Radiology

Philip Murphy - Head, Clinical Imaging, GlaxoSmithKline (GSK)

Title

Breakfast meeting: Dr Stuart Hogarth

Date: Thursday 14th June 2018
Time: 08:30 - 09:30
Venue: Clinical School Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

In June Dr Stuart Hogarth, Lecturer in Sociology of Science and Technology focusing on biomedical innovation, will open the meeting on "Screening for cancer in the era of blockbuster diagnostics – the political economy of diagnostic innovation in comparative perspective".

Title

Seminar by Dr Ranjit Manchanda: "Population based genetic testing strategy for cancer prevention"

Date: Monday 21st May 2018  
Time: 17:30 - 19:00
Venue: Maxwell Centre, Cavendish Laboratory, JJ Thomson Avenue CB3 0HE Cambridge

We are delighted to announce that Dr Ranjit Manchanda of the Barts Cancer Institute Centre for Experimental Cancer Medicine will give a seminar for our programme on 21st May. Dr Manchanda's main research interests are:

  • Risk prediction, screening and prevention of ovarian and endometrial cancer
  • Population based approach(es) to genetic testing for risk stratification and cancer prevention
  • Targeted surgical approaches for prevention of gynaecological cancer
  • Familial gynaecological cancer

He and his team recently published an article in Journal of the National Cancer Institute suggesting that screening the entire population for breast and ovarian cancer gene mutations, as opposed to just those at high-risk of carrying this mutation, is cost effective and could prevent more ovarian and breast cancers than the current approach. Click here for paper.

The talk will be followed by refreshments and the opportunity to network with colleagues.

Title

CRUK Early Detection of Cancer evening

Date: Wednesday 16th May 2018  
Time: 17:30 - 19:00 
Venue: Essex Country Cricket Club, New Writtle Street, Chelmsford  CM2 0PG

An informative evening event, aimed at non-scientists. Speakers will be Dr Sarah Bohndiek, Co-Lead of the Early Detection programme, Dr Charlie Massie and Dr Daniel Munoz-Espin, Group Leaders within the Early Detection programme.

Each speaker will take it in turn to talk about their work in the field of Early Detection, and the difference they hope it will make for future patients. The talks will be followed by a Q&A session with the audience.

Title

DNA Methylation: Bench to bedside - Non-invasive detection of cancer

Date: Friday 11th May 2018  
Time: 14:00 - 15:00 
Venue: Clifford Allbutt Lecture Theatre

A seminar by Dr Andy Feber, Senior Lecturer in the Division of Surgery and Interventional Science at UCL, and leads the genomics research within the Kelly:Feber Lab.

Utilising the latest technologies, the aim of Dr Feber’s research is to define the genomic and epigenomic  alterations involved in cancer development and progression and how these alterations can be used in the diagnosis and treatment of cancer.

His team at UCL have developed the UroMark test that uses the latest technology to analyse over 150 cancer related epigenetic changes in urine samples.  Results to date show that UroMark can detect  bladder cancer with high certainty and is able to differentiate between  bladder cancer and non-cancer conditions such as urinary infection.  The UroMark test is currently in Phase III validation.

Title

Breakfast meeting: Options and considerations for liquid biopsies in cancer early detection

Date: Thursday 10th May 2018
Time: 08:30 - 09:30
Venue: Clinical School Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

In May Dr Charlie Massie, Early Detection Group Leader with the main focus on risk stratification and precision medicine in early stage prostate cancer using non-invasive biomarkers and high-sensitivity genomics approaches, will open the meeting on "Options and considerations for liquid biopsies in cancer early detection".

Title

Early Detection multidisciplinary networking series event 5: Dr Simon Buczacki & Dr Mark Eccleston

Date: Tuesday 1st May 2018  
Time: 17:30 - 19:00 
Venue: Seminar Room 10, Clinical School, Cambridge Biomedical Campus

For this event series we are inviting a STEM scientist or a representative from a relevant local company to pair with a clinical colleague to speak for 15-20 minutes each on their work and where it might be relevant to early cancer detection, and where greater collaboration could assist. 

Speakers at this event are: 
Dr Simon Buczacki - Honorary Consultant Colorectal Surgeon & CRUK Clinical Scientist
Talk title: Barriers to early detection in colorectal cancer

Dr Mark Eccleston - Business Development Director at Volition
Talk title: Nucleosomics - Clinical application of cell free circulating nucleosome profiling in colorectal cancer. 

Merging clinical, biological and physical sciences approaches for cancer research

Date: Tuesday 10th April 2018  
Time: 09:30 - 17:00 
Venue: BMA House, Princes Room, Tavistock Square, London WC1H 9JP

A workshop organised by Cancer Research UK. 

Workshop Overview

The contribution of physics and biology to understanding cancer is long-standing and increasingly well-recognised. Recent major strategic initiatives, including the National Institutes of Health “Physical Sciences in Oncology”, and Cancer Research UK Multidisciplinary award scheme, reflect this increasing recognition and are intended to strengthen collaboration between the physical sciences and biological research communities in order to better address the “Grand Challenges” in cancer research.

In collaboration with the National Institute for Health Research (NIHR) Cancer Research UK and the EPSRC/BBSRC Physics of Life Network, this  workshop will bring together clinicians, biologists and physicists to show-case successful existing collaborations and promote engagement, new ideas and collaborations. This workshop is scheduled in the lead up to Cancer Research UK Multidisciplinary and Early Detection Awards and events.

Title

Cancer and society event series: exploring philosophical and ethical issues around cancer

The CRUK Cambridge Centre Early Detection Programme, in conjunction with the Department of History and Philosophy of Science, the Cambridge Science Festival, CRASSH, the von Hügel Institute and the Cambridge Philosophy and Medicine group present a series of three workshops on philosophical and ethical issues around cancer to be held Cambridge during 2017-2018. Click on the titles of each event for further information and to register.

Philosophy of Cancer: the ethics and epistemology of detection and prevention

Date: 
Wednesday 13th December 2017   
Venue: Department of History and Philosophy of Science, Free School Lane, Cambridge CB2 3RE
Organiser: Dr Stephen John

The sixth sense of the oncologist. How doctors can find cancer earlier and why you may not necessarily want to know (Panel discussion)

Date: Thursday 15th March 2018 (part of Cambridge Science Festival)
Venue: Garden Room, St Edmund's College, Mount Pleasant, Cambridge CB3 0BN
Organiser: Dr Gianmarco Contino
This event is part of the Cambridge Science Festival.

What is so special about cancer? Perspectives from clinical research, philosophy and social sciences

Date: Thursday 5th April 13:30 - Friday 6th April 17:00
Venue: SG1/2 Alison Richard Building, Sidgwick Site
Organiser: Dr Gabriele Badano

Title

Early Detection multidisciplinary networking series event 4: Dr Moritz Gerstung & Dr George Vassiliou

Date: Monday 26th March 2018  
Time: 17:30 - 19:00 
Venue: Maxwell Centre, Cavendish Laboratory, JJ Thomson Avenue CB3 0HE Cambridge

For this event series we are inviting a STEM scientist or a representative from a relevant local company to pair with a clinical colleague to speak for 15-20 minutes each on their work and where it might be relevant to early cancer detection, and where greater collaboration could assist.

Speakers at this event are: 
Dr Moritz Gerstung - Group Leader: Computational cancer biology
"Cancer evolution: Inference and prediction"

Dr George Vassiliou - Group Leader and Honorary Consultant Haematologist
"Identification of healthy individuals at risk of AML"

Science Festival: Listening to light

Date: Sunday 25th March 2018  
Time: 12:30 - 13:15  
Venue: Cancer Research UK, Cambridge Institute, Li Ka Shing Centre, Robinsons Way, CB2 0RE

Michal Tomaszewski explores the various ways we can look inside the human body without touching it, and how different imaging technologies can be used to visualise different aspects of the organism and its function. He focuses on optoacoustic imaging which may help to tell benign from aggressive cancer tumours.

Science Festival: How lab discoveries are leading to earlier detection and more precise treatments for cancer patients

Date: Sunday 25th March 2018  
Time: 11:00 - 15:00  
Venue: Cambridge Academy for Science and Technology, Robinson Way, CB2 0SZ

Join scientists from the Cancer Research UK Cambridge Institute, MRC Cancer Unit and Hutchison/MRC Research Centre to discover how cancer develops, grows, and spreads, and see how researchers and clinicians are developing targeted, personalised therapies and techniques to detect cancer sooner.

Get hands on with games to build your own cell, identify mutations in DNA, try your hand at brain surgery, and learn how new technologies are being used for the early detection and treatment of cancer. Put on a lab coat and isolate DNA or stain tissue samples and look at them under a microscope.

Science Festival: The harms and benefits of breast cancer screening

Date: Tuesday 20th March 2018  
Time: 18:00 - 19:30  
Venue: Mill Lane Lecture Rooms, 8 Mill Lane, CB2 1RW

In recent years the debate about the harms and benefits of breast cancer screening has become increasingly polarised. This expert panel discussion will consider the complexities of this debate from four different disciplinary perspectives. Dr Sian Taylor Philips, an epidemiologist who works with the UK National Screening Committee, will provide insights into the challenges of interpreting the evidence base; Dr Fiona Gilbert will give a clinical perspective and describe new technological options in breast screening, Dr David Spiegelhalter will discuss the challenges of communicating complex risk information to the public in screening programmes and Dr Hogarth will provide a social scientist’s perspective on how the mammography debate has developed since the 1970s.

Title

Breakfast meeting: Genomics/Proteomics and Imaging: Friends or foes in early detection

Date: Thursday 8th March 2018
Time: 08:00 - 09:00
Venue: Clinical School Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

In March Dr Oshaani Abeyakoon, PhD student and Honorary Breast Radiology Consultant at the University of Cambridge will open the meeting on "Genomics/Proteomics and Imaging: Friends or foes in early detection".

Early Detection multidisciplinary networking series event 3: Mr Grant Stewart & Professor Russell Cowburn

Date: Tuesday 27th February 2018  
Time: 17:30 - 19:00 
Venue: Seminar Room 3, Clinical School, Cambridge Biomedical Campus

For this event series we are inviting a STEM scientist or a representative from a relevant local company to pair with a clinical colleague to speak for 15-20 minutes each on their work and where it might be relevant to early cancer detection, and where greater collaboration could assist. The speakers at this event are:

Mr Grant Stewart, Academic urological surgeon with clinical and research expertise in kidney cancer, will speak on: Kidney cancer, a silent killer, in need of an early detection strategy

Professor Russell Cowburn, Department of Physics, with research interests in nanotechnology and its application to magnetism, electronics and optics, will speak on: Magnetic nanostructures for novel cancer therapy and detection

Title

Workshop: The future of in-vitro diagnostics - a regulatory perspective

Date: Thursday 15th February 2018  
Time: 13:00 - 17:30  
Venue: The Gillespie Centre, Clare College, Cambridge

How can regulators strike a reasonable balance between supporting diagnostic innovation and proving rigorous independent evaluation of new diagnostic tests before they enter clinical practice?

In this workshop organised by the Cambridge Academy of Therapeutic Sciences, we will hear from Alberto Gutierrez (former Director of FDA's Office of In Vitro Diagnostic Device Evaluation and Safety), Robyn Meurant (World Health Organisation) and Stuart Hogarth (University of Cambridge) and consider regulatory developments in the context of the response to the genomic revolution in biomedicine as well as the need for safe and effective diagnostics in low and middle-income countries.

Title

Breakfast meeting: Cancer from an evolutionary perspective

Date: Thursday 8th February 2018
Time: 08:00 - 09:00
Venue: Clinical School Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

In February Dr Jamie Blundell, Early Detection Group leader with the aims to understand how mutant clones arise, expand and compete in our tissues as we age, will open the meeting on "Cancer from an evolutionary perspective".

Early Detection Annual Symposium 15th January 2018

Date: Monday 15th January 2018
Time: 14:00 - 18:00
Venue: Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE

The annual symposium is our main showcase event providing an exciting opportunity to meet, hear and network with clinicians and scientists from across the many disciplines involved in cancer early detection work.

This year's keynote speaker is Professor Jessica Zucman-Rossi, Director of functional genomic of solid tumours unit, INSERM, France. She will speak on genomic alterations in early liver tumour development.

Title

Breakfast meeting: Dr Annalise Katz-Summercorn

Date: Thursday 11th January 2018
Time: 08:00 - 09:00
Venue: Cancer Research UK CI Gallery

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting.

In January Dr Annalise Katz-Summercorn, Clinical research fellow in Early Detection in oesophageal adenocarcinoma, will open the meeting on the subject of Screening and pre-invasive GI disease from a surgical perspective.

Title

Breakfast meeting: Initial steps to oncogenesis – modelling via organoids

Date: Thursday 14th December 2017  
Time: 08:00 - 09:00  
Venue: Cancer Research UK CI Gallery

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. 

Our next breakfast meeting will be opened by Dr Mona Shehata, Krishnan-Ang postdoctoral research fellow working on identifying the different cell types within the normal mammary gland, which will allow better knowledge of the cell of origin of breast cancer. The subject of the informal meeting will be: Initial steps to oncogenesis – modelling via organoids.

Early Detection multidisciplinary networking series event 2: Panel discussion - Taking new diagnostic techniques into clinical application

Date: Monday 27th November 2017  
Time: 18:00 - 19:30 
Venue: Postdoc Centre, Biomedical Campus, Hills Road, Cambridge, CB2 0SP

At this event we will have a panel of people with direct experience of taking new diagnostic techniques into clinical application. The panel will be moderated by Dr Dafne Chirivino of Cambridge Enterprise and will include Dr John Pritchard (Entrepreneur in Residence, Cambridge Enterprise), Professor Rebecca Fitzgerald (MRC Cancer Unit), Mr Vincent Gnanapragasam (Department of Surgery) and Dr Anita Marguerie de Rotrou (Office for Translational Research, School of Clinical Medicine). The panel discussion with audience participation will be followed by the opportunity to network further with colleagues over drinks.

Title

Breakfast meeting: Development, validation and potential clinical uses of cancer risk prediction models

Date: Tuesday 14th November 2017 
Time: 08:00 - 09:00 
Venue: Cancer Research UK CI Gallery

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. Our next breakfast meeting is opened by Professor Antonis Antoniou, CRUK Senior Cancer Research Fellow and leads a research group within the Department of Public Health and Primary Care & Dr Juliet Usher-Smith, Clinical Senior Research Associate and Cancer Research UK/BUPA Foundation Cancer Prevention Fellow.

Title

Early Detection multidisciplinary networking series event 1: Dr David Kent & Dr Thierry Savin

Date: Monday 30th October 2017  
Time: 17:30 - 19:00 
Venue: Maxwell Centre, Cavendish Laboratory, JJ Thomson Avenue CB3 0HE Cambridge

For this new event series we are inviting a STEM scientist or a representative from a relevant local company to pair with a clinical colleague to speak for 15-20 minutes each on their work and where it might be relevant to early cancer detection, and where greater collaboration could assist. The speakers at this first event are:

Dr Thierry Savin, University Lecturer in Bioengineering on "modelling cancer invasion as a mechanical instability"

Dr David Kent, Group Leader, Cambridge Stem Cell Institute on "new approaches to expanding blood stem cells outside the body"

Cambridge prostate cancer research forum: research and innovation for early detection and treatment in primary disease

Date: Wednesday 18th October 2017  
Time: 12:00 - 19:30  
Venue: Alice Fisher Lecture Theatre
Cambridge Biomedical Campus, Addenbrooke’s Hospital Site
S Wards Building, Keith Day Rd 
CB2 0SL Cambridge

This meeting will bring together the vibrant and diverse Cambridge research work in prostate cancer. We will have talks from a wide field of researchers working in very different specialities (e.g. clinical trials, radiology, engineering, imaging, bioinformatics) but all focused on driving improvements in outcomes for men suffering from the most common male cancer in the western world. It will be a unique opportunity for networking and exploring synergies in ideas and themes to advance our research in (i) early detection of lethal disease  (ii) better understanding of the biology of primary cancers and (iii) delivering individualised treatment & novel precision medicine approaches.

Title

Breakfast meeting: Early Detection - how histopathology can help

Date: Thursday 12th October 2017
Time: 08:00 - 09:00
Venue: Cancer Research UK CI Gallery

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. In October Dr Maria O'Donovan, Department of Histopathology, will speak on the subject of "Early Detection - how histopathology can help".

Early Detection programme film night and discussion

Date: Thursday 5th October 2017  
Time: 18:00 - 20:30  
Venue: Postdoc Centre, Biomedical Campus
Clifford Allbutt Building (Clinical School entrance) 
Hills Road 
Cambridge CB2 0SP 

We are delighted to announce that the Early Detection Programme will be hosting a film night on Thursday 5th October, at 18.00 in the Postdoc Centre on the Biomedical Campus. We will show the film 50/50 which will be followed by a discussion of some of the issues, led by Early Detection Programme Group Leader Dr Charlie Massie. Refreshments will be provided.

Breakfast meeting: Mr Vincent Gnanapragasam

Date: Thursday 14th September 2017 
Time: 08:00 - 09:00 
Venue: Cancer Research UK CI Gallery

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. Our next breakfast meeting is opened by Mr Vincent Gnanapragasam, University Lecturer in Uro-oncology and Consultant Urologist.

Title

Early Detection Garden Party

Date: Tuesday 18th July 2017
Time: 17:00 -18:30
Venue: Trinity College Cambridge, Fellows' Bowling Green

To celebrate our ongoing achievements, we would like to invite you to the Early Detection programme Garden Party at Trinity College Cambridge.

Breakfast meeting: Stem cell subversion, myeloproliferative neoplasms and the earliest stages of cancer

Date: Thursday 13th July 2017 
Time: 08:00 - 09:00 
Venue: Cancer Research UK CI Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. Our next breakfast meeting is opened by Professor Tony Green, Head of Department; Professor of Haemato-Oncology on the topic "Stem cell subversion, myeloproliferative neoplasms and the earliest stages of cancer"

27th GI Cancer Forum

Date: Wednesday 12th July 2017
Time: 17:30 -19:30
Venue: CRUK Cambridge Institute Lecture Theatre

We are very pleased to invite you to the 27th GI Cancer Forum on July 12th. We have put together a great line up of talks with cutting edge science that will allow us to understand how GI tumours arise and metastasize, and the most advanced application of endoscopic ultrasound in hepatobiliary cancers.

Speakers: 

Dr David Wedge, Oxford University - Heterogeneity and evolution in gastrointestinal cancers.

Dr Maxime Delvincourt, Cambridge University Hospital - Use of EUS in the examination of the bile ducts: past, present and future.

Dr Ayesha Noorani, University of Cambridge - The genomics of metastatic oesophageal adenocarcinoma

At the event we will also announce the exciting GI CANCER FORUM CLINICAL PICTURE CHALLENGE. 

Title

Clinicians meet STEM Scientists: Using genomes and networks to catch cancer early

Date: Thursday 22nd June 2017
Time: 17:30 - 19:00
Venue: Maxwell Centre, Cavendish Laboratory, JJ Thomson Avenue CB3 0HE Cambridge

Join the Early Detection Programme for the 'Clinicians meet STEM Scientists' event series focusing on idea sharing between clinical and physical scientists, in the field of early cancer detection. 

Speakers
Professor Sir Bruce Ponder: Emeritus Professor of Oncology and Founding Director of CRUK Cambridge Centre.

Dr Florian Markowetz: Group Leader, CRUK Cambridge Institute.

Title

Breakfast meeting: CanTest project & Primary Care

Date: Tuesday 6th June 2017 
Time: 08:00 - 09:00 
Venue: Cancer Research UK CI Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. Our next breakfast meeting is opened by Dr Fiona Walter, Principal Researcher in Primary Care Cancer Research and leader of the CanTest team.

Clinicians meet STEM Scientists: Early detection of lung cancer - multidisciplinary challenges and opportunities

Date: Monday 22nd May 2017
Time: 17:30 - 19:00
Venue: Maxwell Centre, Cavendish Laboratory, JJ Thomson Avenue CB3 0HE Cambridge

Join the Early Detection Programme for the 'Clinicians meet STEM Scientists' event series focusing on idea sharing between clinical and physical scientists, in the field of early cancer detection.

Speakers
Dr Frank McCaughan: University Lecturer at the Department of Medicine, University of Cambridge and Honorary Consultant Physician, Cambridge University Hospitals. His laboratory research is focused on understanding the early driver events critical to the development of lung cancer and translating this knowledge into novel approaches to early detection and novel therapeutics or chemoprevention agents.

Dr Carola Schonlieb: Reader in Applied and Computational Analysis, head of the Cambridge Image Analysis (CIA) group at the Department of Applied Mathematics and Theoretical Physics (DAMTP). Her area of expertise is mathematical image reconstruction and image analysis, designed and adapted to various application areas, among them biomedical imaging. In this context we work on high resolution image reconstruction for MR, PET, EM; image reconstruction and analysis for multi-modal imaging; object segmentation, tracking and motion analysis for various imaging modalities.

Breakfast meeting: Thinking big - Cancer early detection in 2027, goals and barriers to progress

Date: Thursday 11th May 2017
Time: 08:00 - 09:00
Venue: Cancer Research UK CI Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. Our next breakfast meeting is opened by Dr David Crosby, CRUK Director of Early Detection and Dr Lauren Kerr, CRUK  Early Detection Programme Manager. The topic of this month's meeting will be "Thinking big: Cancer early detection in 2027 - goals and barriers to progress".

Title

Clinicians meet STEM Scientists: Novel tools for lung cancer early diagnosis and therapy

Date: Monday 24th April 2017
Time: 17:00 - 18:30
Venue: Maxwell Centre, Cavendish Laboratory, JJ Thomson Avenue CB3 0HE Cambridge

Join the Early Detection Programme for the 'Clinicians meet STEM Scientists' event series focusing on idea sharing between clinical and physical scientists, in the field of early cancer detection.

Speakers
Dr Robert Rintoul: Consultant respiratory physician in thoracic oncology at Papworth Hospital, Cambridge and Honorary Visiting Senior Fellow in the University of Cambridge. Robert is currently the lead clinician for cancer at Papworth Hospital and Director of the Papworth Hospital Clinical Trials Unit Collaboration. The focus of his work is around clinical trials and translational research in malignant mesothelioma and the early detection of lung cancer.

Dr Daniel Munoz-Espín: Group Leader, Early Detection Programme. Daniel's laboratory focuses on the fundamental mechanisms and processes that lie at the origin of lung cancer. In particular, the interplay between cellular senescence and cellular plasticity, and the role of cancer stem cells. He aims to translate this knowledge using diagnostic and therapeutic tools based on novel mesoporous silica nanoparticles targeted to senescent cells.

Title

Breakfast meeting: Improving management and diagnosis of Barrett’s oesophagus and early oesophageal carcinoma

Date: Thursday 13th April 2017
Time: 08:00 - 09:00
Venue: Cancer Research UK CI Restaurant.

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. Our next breakfast meeting is opened by Dr Massimiliano Di Pietro, MRC Senior Clinician Scientist and Gastroenterology Consultant at Addenbrooke’s Hospital with a specific interest in early detection of upper gastro-intestinal cancer, on the topic "Improving management and diagnosis of Barrett’s oesophagus and early oesophageal carcinoma".

Title

Love your lifestyle

Date: Sunday 26th March 2017
Time: 11:00 - 16:00
Venue: 
Cancer Research UK CI, Robinson Way, Cambridge CB2 0RE

As part of the Science Festival Cambridge Biomedical Campus open day, from test tube to treatment, join members of the Cambridge Early Detection programme for a fun, interactive game looking at lifestyle factors which could contribute to risk of cancer development. Aimed at children in KS1 and KS2.

Many other activities are planned for this Biomedical Campus wide event. Further details may be found here.

Cambridge Cancer Center Postdoc meeting

Date: Friday 17th March 2017
Time: 09:00 - 18:00, followed by drinks and dinner
Venue: Cancer Research UK CI (dinner at Clare College)

This meeting is aimed at all cancer-related postdocs across Cambridge and has been planned and organised by a committee of postdocs from different departments and institutes. Dr Daniel Muñoz-Espín will be one of the speakers at the event.

Cambridge Science Festival: Is earlier necessarily better?

Date: Wednesday 15th March 2017
Time:
18:00 - 19:30
Venue:
McCrum Lecture Theatre, Eagle Pub Archway (behind Eagle pub), Bene't Street, Cambridge, CB2 3QN

Following our successful Festival of Ideas event on the topic 'Are health tests really a good idea?' we are delighted to announce our plans to reprise this event at the Cambridge Science Festival on 15th March. The format of the event will be similar,showing excerpts from the BBC Horizon programme to stimulate panel and audience discussion, although the focus will be slightly more scientific. The date is set and the venue is booked so if you couldn't be there last time don’t miss it this time!

For more information please visit http://www.sciencefestival.cam.ac.uk/events/earlier-necessarily-better

Title

Breakfast meeting

Date: Thursday 9th March 2017
Time: 08:00 - 09:00
Venue: Cancer Research UK CI Restaurant.

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. If you or your colleagues are involved in early cancer detection in any way please join us for an informal and pleasant start to the day. This month's breakfast meeting is opened by Davina Gale on the topic "Non-invasive cancer diagnostics".

Title

ELRIG Networking Event - Nano delivery of Medicines

Date: Wednesday 8th March 2017
Time: 18:00 - 20:30
Venue: AstraZenenca (Darwin Building), 310 Cambridge Science Park, Milton Road, Cambridge CB4 0FZ

ELRIG is pleased to announce our first free-to-attend networking event of 2017 in the Cambridge area. We continue our focus of developing networking opportunities for unmet scientific or technical challenges. The March event will focus on the challenges of nanodeliveries for therapeutics and will involve informal presentations by guest speakers followed by a free food and drinks reception to facilitate further networking. This event will feature presentations from:

Dr Stefano Pluchino - Department of Clinical Neurosciences University of Cambridge
Dr Daniel Muñoz-Espín - Department of Oncology Hutchison MRC Research Centre

Title

Breakfast meeting

Date: Thursday 9th February 2017
Time: 08:00 - 09:00
Venue: Cancer Research UK CI Restaurant.

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. This month's breakfast meeting is opened by Daniel Muñoz-Espín on the topic "Nanotechnology in cancer diagnosis and therapy".

Title

Early Detection Annual Symposium

Date: Monday 16th January 2017
Time: 14:30 - 18:30
Venue: Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE.

This is an opportunity for researchers across Cambridge and further afield who are engaged with our programme to showcase their latest research and engage in key debates related to early detection.

Title

Breakfast meeting

Date: Thursday 12th January 2017
Time: 08:00 - 09:00
Venue: Cancer Research UK CI Restaurant.

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. This month's breakfast meeting is opened by Sarah Bohndiek on the topic "The role of imaging in early detection".

Title

Breakfast meeting

Date: Thursday 8th December 2016  
Time: 08:00 - 09:00 
Venue: Cancer Research UK CI Restaurant

These monthly meetings are an opportunity for researchers across Cambridge and further afield who are engaged with our programme to network with fellow researchers in an informal setting. This month's breakfast meeting is opened by Maria Alcolea on the topic "Which model systems are useful for early detection?".

Title

Infographics launch party

Date: Tuesday 6th December 2016 
Time: 18:00 - 19:30 
Venue: The Maxwell Centre, Cavendish Laboratory, JJ Thomson Avenue, Cambridge CB3 0HE

The aim of the infographics is to address some of the knowledge gaps that have been identified to exist across the clinical / physical science divide and encourage greater understanding and collaboration.

Click here to download the infographics.

Title

Cambridge Festival of Ideas: Is earlier necessarily better?

Date: Monday 24th October 2016
Time: 17:00 - 18:30
Venue:
McCrum Lecture Theatre, Eagle Passage (behind Eagle Pub), Bene’t Street, Cambridge CB2 3QN

The Cambridge Cancer Centre Early Detection programme invites you to explore the wider issues surrounding earlier cancer detection. Using excerpts from the BBC Horizons programme “Are health tests really a good idea” we will look at the use of cancer screening tests and an invited panel of experts representing the social, legal, anthropological, psychological, ethical and medical fields will debate the issue with the audience.