The Basser Center for BRCA at the Abramson Cancer Center of the University of Pennsylvania, the word's first comprehensive center aimed at advancing research, treatment, and prevention of BRCA-related cancers have announced Cambridge researchers Douglas Easton, PhD and Antonis Antoniou, PhD as the recipients of the seventh annual Basser Global Prize. Both professors work in the department of Public Health and Primary Care at the University of Cambridge and they are both members of the Cancer Research UK Cambridge Centre.
Each year a leading scientist who has conceptually advanced BRCA 1/2-related research is reconised with the Basser Global Prize.
The research of Professor Easton and Antoniou focuses on genetic susceptibility to common cancers with the goal of identifying and characterising genetic variants associated with cancer risk, with a particular emphasis on hormone-related cancers. Much of their work has focused on characterising the cancer risk for BRCA1 and BRCA2 mutation carriers, the analysis of genome-wide association studies (GWAS) in breast and other cancers, and using this information to personalise cancer risk prediction.
Antonis Antoniou: “The Basser Global Prize will be critical in supporting our research on the prevention and early detection of cancer in BRCA1 and BRCA2 mutation carriers. We aim to achieve this through the integration of epidemiological studies with novel molecular and functional analyses.”