Early Detection researchers recognised through the Senior Academic Promotions process

Published: 26th June, 2020

We are absolutely delighted to announce that Sarah Bohndiek, Co-lead of the Early Detection Programme, will be promoted to Professor from October. Following her PhD at UCL, Sarah began her postdoctoral research in Cambridge under Kevin Brindle in 2008. After a period of 2 years at Stanford under Sam Gambhir, she returned to Cambridge in 2013 as a University Lecturer in the Department of Physics, and was jointly appointed as a group leader at the CRUK Cambridge Institute in 2014.

Highly sensitive blood test to monitor cancer

Published: 18th June, 2020

A new method of analysing cancer patients’ blood for evidence of the disease could be up to ten times more sensitive than previous methods according to new research funded by Cancer Research UK and published in Science Translational Medicine on Wednesday.

In the coming years, this method and others based on this approach could lead to tests that more accurately determine if a patient is likely to relapse after having treatment, and could pave the way for the development of pinprick home blood tests to monitor patients

Cambridge Researchers have been awarded ACED funding

Published: 22nd May, 2020

In its May International Alliance for Cancer Early Detection (ACED) newsletter, Cancer Research UK is showcasing the first researchers who received Alliance funding. Four projects that are collaborations with members of the Cancer Research UK Cambridge Centre have been awarded ACED Pilot funding and one researcher from the University of Manchester has received the ACED Skills exchange and development travel award to visit Cambridge University.

Potentially cancerous cells kept in check by competitive neighbours, study of oesophagus finds

Published: 20th May, 2020

The expansion of ‘mutant’ cells that could lead to cancer is often kept in check by their neighbours, research from the Wellcome Sanger Institute, the University of Cambridge and their collaborators has found. The team discovered that when equally-matched cells in the oesophagus of mice coincided, they acted as a brake on one another’s growth.

The study, published 18 May 2020 in Nature Genetics, describes the ‘rules of the game’ of competition between oesophageal cells for the first time. By understanding these rules, the hope is that therapies can be developed to reduce the competitiveness of mutant clone cells that are more likely to become cancerous.

Early Detection Researchers in COVID-19 response

Published: 18th May, 2020

It has been truly impressive to read how many Cambridge researchers are stepping up to contribute to the national response to COVID-19 and the Early Detection Programme is no different.

New Open Lab initiative to connect researchers

Published: 18th May, 2020

Are you looking for new opportunities to exchange ideas and interact more closely with other research groups?

The aim of the Open Lab Initiative is to connect CRUK Centre Network research groups with mutual or complementary interests and expertise, from across the UK, to spark creative discussions, generate novel scientific ideas, and establish new research collaborations during the coronavirus (COVID-19) pandemic and beyond.

Dr Harveer Dev takes up post as Early Detection Clinical Lecturer

Published: 01st April, 2020

On 1st April Dr Harveer Dev commenced his Clinical Lectureship post with the Early Detection Programme. Harveer, a clinical urologist by training, has completed five years of postgraduate basic research developing knowledge and technical capabilities in the field of DNA repair in cancer. His primary research aim as a Clinical Lecturer is to explore early intervention with DNA damage response, targeting agents in high risk, early stage prostate cancers to address the key question of "how can we distinguish indolent from aggressive disease?"

Blundell Group publish in Science

Published: 27th March, 2020

Congratulations to the Blundell Group at the CRUK Cambridge Centre Early Detection Programme whose first paper is published in Science today. The paper, The evolutionary dynamics and fitness landscape of clonal hematopoiesis, addresses a key question in the field of early cancer detection, namely which specific mutations enable cells to expand most rapidly, and thus might confer the highest risk of cancer?

Dr Gahee Park invited to speak at Advances in Genome Biology and Technology 2020 meeting

Published: 11th March, 2020

Postdoctoral Researcher in the Massie Lab, Dr Gahee Park, was invited to speak at the Advances in Genome Biology and Technology (AGBT) 2020 meeting held in Marco Island, Florida at the end of February. Gahee's talk, entitled Targeted Epigenome Sequencing of cfDNA to Improve Sensitivity for Early Cancer Detection explains their findings, using proprietary technology, that DNA methylation changes are robust cancer-specific markers. See Gahee's full talk on YouTube.

Sarah Bohndiek's twelve tips for engaging with biologists

Published: 20th January, 2020

In an interview with Biologist Kenneth Kosik for Nature Career Column, Dr Sarah Bohndiek gives her twelve tips for engaging with biologists.

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