British Society of Gastroenterology Trainees Podcast: Interview with Professor Rebecca Fitzgerald

Published: 07th July, 2021

Co-lead of the Early Detection Programme, Professor Rebecca Fitzgerald, was one of the prominent gastroenterologists interviewed by the British Society of Gastroenterology (BSG) Trainees for their podcast series.

Research Alert: Targeting kidney cancer screening at people at higher risk shows promise and would be acceptable to the public

Published: 16th June, 2021

Kidney cancer is the 7th most common cancer in the UK and the incidence is projected to rise by 26% between 2014 and 2035, representing one of the fastest accelerating cancers within that timeframe. The disease is usually curable if identified early.

This research briefing describes recent work at the University of Cambridge on kidney cancer screening, led by Dr Juliet Usher-Smith and Professor Grant Stewart. A screening programme for kidney cancer might diagnose the disease at an earlier stage, reduce the prevalence of metastatic tumours at diagnosis, decrease the expenditure related to systemic therapies and improve survival.

Mobile screening unit, which uses a 'sponge on a string' to check for early signs of oesophageal cancer, has launched in Cambridge

Published: 09th June, 2021

A new device to detect the early signs of cancer is being offered for the first time to GP patients in the UK, via a special mobile testing unit.

Professor Fitzgerald elected as EMBO member for outstanding life science research

Published: 09th June, 2021

Congratulations to Professor Rebecca Fitzgerald, who has been elected as an EMBO member in recognition of her outstanding life science research.

Research Alert from Primary Care Unit: Improving screening for bowel cancer using risk stratification

Published: 07th June, 2021

Age is the most important risk factor for bowel cancer but many genetic and lifestyle risk factors have been identified. There is interest in whether information about these factors could be used to improve screening programmes for bowel cancer. In this research, funded by Bowel Cancer UK and led by Dr Juliet Usher-Smith, scientists at the Universities of Cambridge and Sheffield have been assessing the potential value of identifying people at higher and lower risk of bowel cancer – a process called risk stratification.

Study shows the potential of multispectral cameras to detect and treat cancer

Published: 02nd June, 2021

The results of a pilot first-in-human clinical trial demonstrate that using a spectral endoscopy, rather than conventional white-light, gives a more detailed, high-contrast image, helping to differentiate between healthy and cancerous cells more easily.

Professor Fitzgerald contributes to parliamentary report on the 'Future of Disease Prediction and Diagnosis'

Published: 04th May, 2021

Rebecca Fitzgerald, Professor of Cancer Prevention and co-lead of the Early Detection Programme, was one of the experts consulted by parliament to consider how to prepare for a changing world.

As part of the Parliamentary Office of Science and Technology's Horizon Scanning process, 30 areas of change were identified that will help the UK Parliament prepare for the future.

New cancer algorithm flags genetic weaknesses in tumours

Published: 26th April, 2021

A new study, led by Dr Serena Nik-Zainal, has shown a new way to identify tumours that could be sensitive to particular immunotherapies. Developed using data from thousands of NHS cancer patient samples sequenced through the 100,000 Genomes Project, the MMRDetect clinical algorithm makes it possible to identify tumours that have ‘mismatch repair deficiencies’ and then improve the personalisation of cancer therapies to exploit those weaknesses.

Artificial intelligence could ease pressures on diagnostic services for precancerous condition, Barrett’s oesophagus

Published: 15th April, 2021

Artificial intelligence (AI) could help free up pathologist time and allow them to focus on diagnosing the most tricky cases of Barrett’s oesophagus, according to a Cancer Research UK-funded study published in Nature Medicine today (15th April 2021).

Professor Fitzgerald interviewed in CAM; the extraordinary story of the Cytosponge

Published: 07th April, 2021

In an interview in the Cambridge Alumni Magazine, Professor Rebecca Fitzgerald explains the remarkable story of the cytosponge and how her literary hero Sherlock Holmes has inspired her to tackle the challenges of early cancer detection.

Read the full 'Cytosponging' feature in CAM.

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