Cambridge Researchers have been awarded ACED funding

Published: 22nd May, 2020

In its May International Alliance for Cancer Early Detection (ACED) newsletter, Cancer Research UK is showcasing the first researchers who received Alliance funding. Four projects that are collaborations with members of the Cancer Research UK Cambridge Centre have been awarded ACED Pilot funding and one researcher from the University of Manchester has received the ACED Skills exchange and development travel award to visit Cambridge University.

Potentially cancerous cells kept in check by competitive neighbours, study of oesophagus finds

Published: 20th May, 2020

The expansion of ‘mutant’ cells that could lead to cancer is often kept in check by their neighbours, research from the Wellcome Sanger Institute, the University of Cambridge and their collaborators has found. The team discovered that when equally-matched cells in the oesophagus of mice coincided, they acted as a brake on one another’s growth.

The study, published 18 May 2020 in Nature Genetics, describes the ‘rules of the game’ of competition between oesophageal cells for the first time. By understanding these rules, the hope is that therapies can be developed to reduce the competitiveness of mutant clone cells that are more likely to become cancerous.

Early Detection Researchers in COVID-19 response

Published: 18th May, 2020

It has been truly impressive to read how many Cambridge researchers are stepping up to contribute to the national response to COVID-19 and the Early Detection Programme is no different.

New Open Lab initiative to connect researchers

Published: 18th May, 2020

Are you looking for new opportunities to exchange ideas and interact more closely with other research groups?

The aim of the Open Lab Initiative is to connect CRUK Centre Network research groups with mutual or complementary interests and expertise, from across the UK, to spark creative discussions, generate novel scientific ideas, and establish new research collaborations during the coronavirus (COVID-19) pandemic and beyond.

Dr Harveer Dev takes up post as Early Detection Clinical Lecturer

Published: 01st April, 2020

On 1st April Dr Harveer Dev commenced his Clinical Lectureship post with the Early Detection Programme. Harveer, a clinical urologist by training, has completed five years of postgraduate basic research developing knowledge and technical capabilities in the field of DNA repair in cancer. His primary research aim as a Clinical Lecturer is to explore early intervention with DNA damage response, targeting agents in high risk, early stage prostate cancers to address the key question of "how can we distinguish indolent from aggressive disease?"

Blundell Group publish in Science

Published: 27th March, 2020

Congratulations to the Blundell Group at the CRUK Cambridge Centre Early Detection Programme whose first paper is published in Science today. The paper, The evolutionary dynamics and fitness landscape of clonal hematopoiesis, addresses a key question in the field of early cancer detection, namely which specific mutations enable cells to expand most rapidly, and thus might confer the highest risk of cancer?

Dr Gahee Park invited to speak at Advances in Genome Biology and Technology 2020 meeting

Published: 11th March, 2020

Postdoctoral Researcher in the Massie Lab, Dr Gahee Park, was invited to speak at the Advances in Genome Biology and Technology (AGBT) 2020 meeting held in Marco Island, Florida at the end of February. Gahee's talk, entitled Targeted Epigenome Sequencing of cfDNA to Improve Sensitivity for Early Cancer Detection explains their findings, using proprietary technology, that DNA methylation changes are robust cancer-specific markers. See Gahee's full talk on YouTube.

Sarah Bohndiek's twelve tips for engaging with biologists

Published: 20th January, 2020

In an interview with Biologist Kenneth Kosik for Nature Career Column, Dr Sarah Bohndiek gives her twelve tips for engaging with biologists.

Call for Abstracts: Early Detection 5th Annual Symposium

Published: 25th October, 2019

The CRUK Cambridge Centre fifth annual symposium will take place on Monday 27th January 2020 in the CRUK Cambridge Institute. We invite PhD students, postdocs, junior group leaders and other researchers involved in all aspects of early detection research to submit abstracts to be considered for an oral and/or a poster presentation (A1 portrait) at the event. Poster abstracts will also be considered for a 5-minute poster flash talk during the symposium.

Early Detection Programme in the press because of ACED Alliance announcement

Published: 22nd October, 2019

After the announcement of the International ACED Alliance on Monday, there has been a lot of media coverage for the Alliance and for the Early Detection Programme as part of it. This news item contains a list with some of the UK press coverage.

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