Professor Tony Green

Professor Tony Green

Department of Haematology
Wellcome - MRC Cambridge Stem Cell Institute

Head of department
https://www.stemcells.cam.ac.uk/research/pis/green

The JAK/STAT pathway has essential roles in several aspects of metazoan biology including haematopoiesis and stem cell function. Somatic mutations affecting this pathway occur in multiple tumour types and are especially common in human myeloproliferative neoplasms. The Green lab is studying the molecular and cellular mechanisms whereby aberrant JAK/STAT signalling subverts haematopoiesis and results in a myeloproliferative neoplasm